Pharmacology DesOwen
Pharmacological action – anti-local, antiallergic, vasoconstrictor. Induces the formation of lipokortina inhibiting the activity of phospholipase A2, inhibits the synthesis of PG and LT. Reduces vascular permeability, chemotaxis, contributes to the stabilization of lysosomes.
Application of the substance DesOwen
Inflammatory diseases of the anterior segment and its appendages: allergic conjunctivitis, blepharitis scaly, episcleritis, recurrent iritis, iridocyclitis (posterior segment eye); postoperative and post-traumatic inflammation of the eye, thermal and chemical destruction of the cornea.
Contraindications DesOwen
Hypersensitivity, increased intraocular pressure, conjunctivitis with ulcerative keratitis (including in the initial stage of a positive test with fluorescein), viral diseases of the cornea (also caused by Herpes simplex, the stage of ulceration), tuberculosis, eye, eye mycosis, purulent ophthalmia, purulent conjunctivitis, purulent and herpetic blepharitis, stye.
Restrictions on the use DesOwen
Pregnancy, breast feeding, childhood (safety and efficacy in children not identified).
Pregnancy and breast feeding DesOwen
During pregnancy and lactation is possible only on strict indications and under medical supervision.
Category of the fetus by FDA – C.
Side effects of substance DesOwen
Local reactions: tingling or burning sensation in the eye, with prolonged use – increased intraocular pressure, reduced visual acuity and fields, optic nerve damage, cataracts, corneal perforation, development of fungal infection.
Dosage and administration DesOwen
Topically. Eye drops – 1-2 drops or DesOwen eye ointment (for laying the eyelid) 3-4 times a day. Perhaps the combined use of: for the day – eye drops at night – ointment treatment – 2 weeks.
Precautions DesOwen
If necessary, continue treatment for more than 2 weeks, and requires systematic monitoring of intraocular pressure.
Not recommended for use in damage and abrasions of the cornea (slows healing, promotes the spread of infection).
Be wary of disease, accompanied by thinning of the cornea (corneal perforation is possible.)
In viral diseases caused by Herpes simplex, used only in combination therapy together with antiherpetic drugs and only under the constant supervision of an ophthalmologist.
Cautions DesOwen
Can be applied to the drivers of vehicles and people skills is associated with increased concentration.
